Formulation and Evaluation of Herbal Gel Containing Kigelia africana(lam.) Benth., Fruits Extract

Authors

  • R. Bhramaramba Sir C R Reddy college of pharmaceutical sciences, Santhi Nagar, GNT Road, Eluru, Andhra Pradesh Author
  • M. Harsha Vardahan Chowdary Sir C R Reddy college of pharmaceutical sciences, Santhi Nagar, GNT Road, Eluru, Andhra Pradesh Author
  • K. Bharath Lova Sir C R Reddy college of pharmaceutical sciences, Santhi Nagar, GNT Road, Eluru, Andhra Pradesh Author
  • A. Nagarjuna Sir C R Reddy college of pharmaceutical sciences, Santhi Nagar, GNT Road, Eluru, Andhra Pradesh Author

DOI:

https://doi.org/10.53555/nnas.v2i4.680

Keywords:

Kigelia africana(Lam.) Benth., aqueous extract, Carbapol 940, herbal Gel, skin irritation

Abstract

Herbal medicine has become an item of global importance, both medicinal and economical. Although usage of these herbal medicines has increased, their quality, safety, and efficiency are serious concerns in industrialized and developing countries. The present research has been undertaken with the aim to formulate and evaluate the herbal gel containing Kigelia africana (Lam.) Benth. fruit extract. The gel formulation was designed by using Carbapol 940, Kigelia africana (Lam.) Benth. fruit extract, propylene glycol, methyl paraben, propyl paraben, and the required amount of distilled water. The skin pH (6.8-7.1) was maintained by dropwise addition of triethanolamine. The physicochemical parameters of formulations (pH, spreadability, stability, etc.) were determined. Stability studies have been carried out as per ICH guidelines for 3 months at different temperatures and humidity. The results showed that a formulation containing Kigelia africana (Lam.) Benth. fruit extract shows better stability. Further formulations have been studied for skin irritation on an animal model (rat), and the results showed that there was no skin irritation to animals.

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Published

2015-04-30

Issue

Vol. 2 No. 4 (2015): Journal of Advance Research in Applied Science (ISSN: 2208-2352)

Section

Articles

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Copyright (c) 2015 R. Bhramaramba, M. Harsha Vardahan Chowdary, K. Bharath Lova, A. Nagarjuna (Author)

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How to Cite

Formulation and Evaluation of Herbal Gel Containing Kigelia africana(lam.) Benth., Fruits Extract. (2015). Journal of Advance Research in Applied Science (ISSN 2208-2352), 2(4), 08-12. https://doi.org/10.53555/nnas.v2i4.680